Pumpkin (Shapiro), the last girl on earth and sole survivor of a humanity-ending plague, scavenges the wasteland for supplies on the eve of Halloween. Pumpkin’s lonely holiday ritual is interrupted by the arrival of a savage gang of raiders at her doorstep, led by the fearsome Thalia (Sossamon). Outnumbered and armed with candy, wit and weapons, Pumpkin must ferociously fight back to survive the night.